Scientific Keynote Presentation: Evolution of Therapy in Sickle Cell Disease

Learning Objectives:

• Understand how our growing understanding of SCD pathophysiology is leading to development of new targeted approaches to treatment.
• Understand how pharmacotherpaeutics either currently available or in development address the pathophysiology of SCD.
• Understand why drugs with some apparent clinically relevant benefits may nonetheless exacerbate other aspects of SCD.